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deskgameProfit boosts: Get enhanced odds on select betting markets. deskgameAs the NFL Week 11 odds open, sportsbooks view Philadelphia as 3 to 3.5-point favorites, depending on the platform. The over/under for the game is between 49 and 49.5. deskgameThe Bulldogs navigated the nation’s toughest schedule, per ESPN’s Power Index. They rank 47th in the nation in offensive yards per game, and 23rd in points per allowed (20.4). Notre Dame’s formidable defense is third in the nation in points allowed (13.6) and the offense ranks third in the nation in points scored (39.8). deskgameThe Lions’ standout RB is up to 15 scrimmage TDs on the season, which is tied for second-most in the NFL. San Francisco’s reputation as a tough team to rush for a TD against is based only on the past. The 49ers have allowed 15 rushing TDs to RBs this season, tied for third-most in the league.